Myelodysplasia, also known as myelodysplastic syndrome (MDS), is a group of disorders caused by poorly formed or dysfunctional blood cells. It primarily affects the bone marrow, where blood cells are produced. In MDS, the bone marrow produces abnormal cells that don’t mature properly, leading to a shortage of healthy blood cells12.
Key Points about Myelodysplasia:
- Types: There are several types of MDS, classified based on which blood cells are affected and the presence of genetic abnormalities2.
- Symptoms: Common symptoms include fatigue, frequent infections, and easy bruising or bleeding due to low counts of red blood cells, white blood cells, and platelets12.
- Progression: MDS can progress slowly or rapidly and, in some cases, may develop into acute myeloid leukemia (AML)13.
- Treatment: Treatment options vary depending on the type and severity of MDS and may include medications, blood transfusions, and bone marrow transplants
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